Autoimmune addison disease and premature ovarian failure
نویسندگان
چکیده
منابع مشابه
Autoimmune premature ovarian failure
Premature ovarian failure (POF), also termed as primary ovarian insufficiency (POI), is a highly heterogenous condition affecting 0.5-3.0% of women in childbearing age. These young women comprise quite a formidable group with unique physical and psychological needs that require special attention. Premature ovarian senescence (POS) in all of its forms evolves insidiously as a basically asymptoma...
متن کاملTreatment of autoimmune premature ovarian failure.
There is no known immunosuppressive therapy for autoimmune premature ovarian failure that has been proven safe and effective by prospective randomized placebo-controlled study. Nevertheless, immunosuppression using corticosteroids has been used on an empirical basis for this condition. Here we present two cases of young women with premature ovarian failure who were treated with glucocorticoids ...
متن کاملPremature Ovarian Failure in Autoimmune Polyglandular Syndrome
Autoimmune polyglandular syndromes are a rare group of disorders of which Type II is the commonest. Premature ovarian failure is a minor feature of the disorder. The identification of the syndrome may take several years and different medical specialties need to be involved in the diagnosis and management of the case. The present case report describes the difficulties encountered in the diagnosi...
متن کاملOvarian aging and premature ovarian failure.
Physiological reproductive aging occurs as a result of a decrease in the number and quality of oocytes in ovarian cortex follicles. Although the reason for the decrease in the quality of the pool and follicular oocytes is not fully understood, endocrine, paracrine, genetic, and metabolic factors are thought to be effective. Nowadays, in order to understand the mechanisms of ovarian aging, genom...
متن کاملPremature ovarian failure
Premature ovarian failure is defined as a primary ovarian defect characterized by absent menarche (primary amenorrhea) or premature depletion of ovarian follicles/arrested folliculogenesis before the age of 40 years (secondary amenorrhea). Hormonally, POF is defined by abnormally low levels of estrogen and high levels of FSH, which demonstrate that the ovaries are no longer responding to circul...
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ژورنال
عنوان ژورنال: Nature Reviews Endocrinology
سال: 2011
ISSN: 1759-5029,1759-5037
DOI: 10.1038/nrendo.2011.117